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In sum, it is likely that niacin acts through several neuroprotective mechanisms to modify the pathology of PD, including altered inflammatory state, dopamine supplementation, and reduced oxidative stress (Fig
As well as chemical targeting, enzymatic targeting is another challenging strategy and cyst(e)inase-mediated depletion of serum cysteine and cystine pools has already been demonstrated to suppress the growth of tumours in different animal models
Anticancer Drugs 15, 779785
