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In turn, RAC2-GTP binds to and activates several downstream effector molecules such as p21-activated kinase 1 (PAK1) to drive cellular functions such as ROS production (68, 69)

10.1038/s41598-018-31749-z 82 KarlerR.TurkanisS

Peng et al., 2022) (Figure 2)

In spite of that, a generally acceptable consensus defines a stem cell as an undifferentiated cell that has capacity to self-renew, for production of progeny in at least two lineages, for long-term tissue repopulation after transplantation, and for serial transplantability
