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4 The increase in TAp73 in p53 wt MCF-7 p53 dom/neg MDD2 breast cancer cells suggested some degree of post-binding stabilization, independent of p53 status

17, 18, 19 In our study, using four distinct cell lines, two with wild-type p53 and two with mutated p53, no correlation between p53 status and cisplatin cellular sensitivity was observed: the cell viability, as determined by XTT assays, and apoptosis (sub-G1) results revealed that U251MG cells (p53mt) are highly sensitive to cisplatin, in contrast to U138MG, which is also a p53 mutant cell line

A trained clinician should demonstrate proper injection technique to minimize local irritation
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Although preliminary evidence suggests potential benefits for sports performance, oxidative stress reduction, and cognitive function, most studies are small-scale, preclinical, or observational
