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However, the use of nootropics by healthy individuals is of great concern due to the lack of clinical evidence regarding their efficacy, safety, and social consequences, especially in long-term use [2,8]

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Department of Health and Human Services (HHS) recently announced policy changes designed to make information about clinical trials of investigational drugs, biologics and products more widely available to the public, issuing amended rules that specify the requirements for registering clinical trials and for submitting summary results to its ClinicalTrials.gov website

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