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GEMINI I TRIAL PRIMARY END POINTS Overall population compared with placebo ENTYVIO-TREATED PATIENTS ACHIEVED RAPID RESPONSE AND LONG-TERM REMISSION RAPID RESPONSE AND LONG-TERM REMISSION Clinical response at Week 6 1 * Clinical remission at Week 52 1 ENTYVIO IV Placebo CI=confidence interval

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Peptides like Ipamorelin , CJC-1295 , Sermorelin , Tesamorelin , and Hexarelin are among the most studied GHSs

Unlike in both normal and cancer-differentiated cells [150], activating mutations in the WNT/ -catenin pathway [229] or overexpression of mutated -catenin in SOX2-expressing SPCs resulted in a homogenous cancer formation [230]