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Nature 559 , 135139 (2018)
Figure 4 4 Therapeutic strategies targeting ferroptosis in Alzheimers disease 4.1 Therapeutic strategies targeting iron homeostasis In AD, the disruption of iron homeostasis is considered a pivotal upstream event that triggers ferroptosis activation and drives pathological spread (Figure 5)
In primary cilia, reduced glutamylation perturbs intraflagellar transport and ciliary signaling and contributes to ciliopathies including Joubert syndrome and retinal degeneration
Baldassari, S
