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By-products of this process are potentially harmful molecules known as reactive oxygen species (ROS)
10.1007/978-3-642-25950-0_6 Handb
Clinical trials of AOD-9604 lasting up to 24 weeks demonstrated no cardiovascular adverse events and excellent overall tolerability

Peak fractions were pooled and concentrated to ~1.9 mg/ml and digested overnight at 4 C with thrombin at a 1:100 wt/wt ratio
